![]() Apply enough silver sulfadiazine to cover the affected area evenly. Take care to keep the treatment area as clean as possible to prevent further infection.Ĭlean the area to be treated as directed by your doctor. The person applying silver sulfadiazine to burn wounds should wear sterile disposable gloves. Wash your hands before and after applying silver sulfadiazine cream. Do not use silver sulfadiazine topical in larger or smaller amounts or for longer than recommended. How should I use silver sulfadiazine topical?įollow all directions on your prescription label. You may report side effects to FDA at 1-80. Call your doctor for medical advice about side effects. This is not a complete list of side effects and others may occur. Severe skin reaction-fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. Liver problems-nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes) or Kidney problems-red or pink urine, little or no urinating, swelling, rapid weight gain Pale or yellowed skin, dark colored urine, fever, confusion or weakness Sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing Įasy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin Silver sulfadiazine topical may cause serious side effects. Lidocaine acute pain chronic pain topical anesthetic wound healing.Get emergency medical help if you have any of these signs of an allergic reaction: hives difficult breathing swelling of your face, lips, tongue, or throat.Īlthough the risk of serious side effects is low when silver sulfadiazine is applied to the skin, side effects can occur if the medicine is absorbed into your bloodstream. The treatment of painful wounds with 5% Lidocaine Cream for 14 days resulted in reduced pain intensity, and showed high safety and tolerability. 13 patients presented a total of 25 adverse events, 4 of them were related to the treatment. 9 patients prematurely stopped the treatment for healing (n = 4), wound improvement (n = 2) and adverse events related to the treatment. The intensity of pain significantly decreased from the baseline level established at the beginning of treatment (mean score 6.7 - 1.90) - to the level at end of treatment (3.0 - 2.23- p < 0.0001). The wounds included traumatic wounds (n = 39), venous ulcers (n = 25), post-surgical wounds (n = 6) pyoderma gangrenosum (n = 6), vasculitis (n = 1) and pressure ulcer (n = 1). Seventy-eight patients had a median age of 67.5 years (range 18-96 years). Clinical aspects and adverse events were also collected. The primary outcome of the study was establishing the wound pain relief based on the results of 5-VRS and pain intensity based on the 11-NPRS testing from baseline to the end of treatment. All medications and adverse events were evaluated in a daily diary. ![]() Patients' perception of pain was recorded by, using the 5-point Visual Rate Scale and the 11-point Numerical Pain Rating Scale. The study included 78 patients with painful wounds treated with 5% Lidocaine cream for two weeks in two Italian Hospitals. ![]() This prospective, multicentre study examined the effects of 5% lidocaine cream on wound pain relief. ![]() Lidocaine hydrochloride is frequently used for management of painful wounds.
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